SUCESORES DE ARTURO CARBONELL, S.L. CTRA. NACIONAL 301 KM 384 P.O. BOX, 4 TEL.: 34 968 643 745 - 34 968 643 774 FAX: 34 968 643 774 30500 MOLINA DE SEGURA (MURCIA -SPAIN)

Ground curcuma in sacks of 25 kg.

Curcuma longa L., it is a plant of Asian origin very commonly used like a spice in the Asian culture. The main component is the curcumina, one of the active ingredients responsible for its biological activity. It is known that this substance is stable in the stomach and in the small intestine; its high lipofilia allows him/her a gastrointestinal quick absorption for passive diffusion. After their administration, it is metabolized and excreted mainly by bile and grounds, and also for urine. Their main metabolitos is also bioactivos. From old, many properties have been described for the extracts of Curcuma longa and for the curcumina. It is known their antibacterial activity, antifúngica and antiparasitaria, and recently their capacity has been demonstrated to inhibit the integrasa of the HIV-1. Specific effects have also been demonstrated in other fabrics and organs, as the skin, the gastrointestinal and breathing system and in the liver. All these properties are due to different action mechanisms. It has been demonstrated that the cúrcuma possesses anti-inflammatory effects, through the modulation of the metabolism of the eicosanoides, he/she has capacity inmunomoduladora, mainly altering the profile of the citoquinas Thl of the linfocitos T helper, and activity hipolipidémica, diminishing the cholesterol, the triglycerides and the plasmatic fosfolípidos as well as in LDL. There are many studies that demonstrate the capacity of the cúrcuma to stabilize membranes and to prevent the peroxidación lipídica, a fundamental process in the establishment, the progression and the complications of many pathologies like the hepatic, renal, cardiovascular illnesses, neurodegenerativas, in the diabetes and in the waterfalls. The last investigations on the biological effects of the cúrcuma extracts and of the curcuminoides they are guided to study their anticancerous activity, mainly in front of the skin cancer, colon and duodenum.